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Peptide record

TPDB08745

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08745
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LLGMIPVAIKAISALSKL
Physicochemical Analysis
C86H156N20O21S1
RNDCEQHFTWY
L
1838.37
10.60
2
0
12
+2
-1.14
1.600
184.44
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
4
L
2
K
1
M
0
F
1
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 4 K: 2 M: 1 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C86H156N20O21S1
1838.37
10.60
+2
-1.14
1.600
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>512 µM

Target

E.coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram- E.coli (MIC >512 uM), P.aeruginosa (MIC >512 uM), Gram+ S. aureus MRSA (MIC 8 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
>512 µM

Target

P.aeruginosa

Source & Reference

dbAMP

Other

active against Gram- E.coli (MIC >512 uM), P.aeruginosa (MIC >512 uM), Gram+ S. aureus MRSA (MIC 8 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
8 µM

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP

Other

active against Gram- E.coli (MIC >512 uM), P.aeruginosa (MIC >512 uM), Gram+ S. aureus MRSA (MIC 8 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
>512 µM

Target

E.coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram- E.coli (MIC >512 uM), P.aeruginosa (MIC >512 uM), Gram+ S. aureus MRSA (MIC 8 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
>512 µM

Target

P.aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E.coli (MIC >512 uM), P.aeruginosa (MIC >512 uM), Gram+ S. aureus MRSA (MIC 8 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
8 µM

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E.coli (MIC >512 uM), P.aeruginosa (MIC >512 uM), Gram+ S. aureus MRSA (MIC 8 uM).
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
102.2 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 102.2 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Targeted Modification of a Novel Amphibian Antimicrobial Peptide from Phyllomedusa tarsius to Enhance Its Activity against MRSA and Microbial Biofilm. | Front Microbiol | 2017