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Peptide record

TPDB08724

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08724
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KNLRRIIRKGIHIIKKYF
Physicochemical Analysis
C108H186N34O21
ADCEQMPSTWV
I
2296.88
12.16
8
0
8
+7
3.60
-0.467
130.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
64.87
2
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
5
I
1
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 5 L: 1 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
18
C108H186N34O21
2296.88
12.16
+7
3.60
-0.467
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>50 µM
Hemolytic Cytotoxic
50% Hemolysis | >50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane interactions of novicidin, a novel antimicrobial peptide: phosphatidylglycerol promotes bilayer insertion. | J Phys Chem B | 2010
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis