Peptide record

TPDB08709

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08709
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
WCRRLCYKQRCVTYCRGR
Physicochemical Analysis
C99H160N36O23S4
ANDEHIMFPS
R
2350.83
10.10
6
0
5
+6
0.59
-0.917
37.78
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
8730
371.36
8
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
0
E
1
Q
1
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
1
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 2 V: 1
Chemical Descriptors
18
C99H160N36O23S4
2350.83
10.10
+6
0.59
-0.917
Evidence Records 1 records
Evidence 1 Activity

Activity

32% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
32% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship of Trp-containing analogs of the antimicrobial peptide gomesin. | J Pept Sci | 2014