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Peptide record

TPDB08703

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08703
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LNALKKVFQKIHEAIKKI
Physicochemical Analysis
C100H173N27O23
RDCGMPSTWY
K
2121.64
10.71
6
1
9
+4
5.48
-0.083
135.56
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
1
Q
0
G
1
H
3
I
2
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 3 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C100H173N27O23
2121.64
10.71
+4
5.48
-0.083
Evidence Records 2 records
Evidence 1 Activity

Activity

1.33% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
1.33% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018
Evidence 2 Activity

Activity

3.5% Cytotoxicity
Toxicity
100 µM
Cytotoxic
3.5% Cytotoxicity | 100 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018