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Peptide record

TPDB08697

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08697
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GMASLWAKVLPHVVKLIK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C95H160N24O20S1
RNDCEQFTY
LKV
1990.52
10.84
4
0
11
+3
-0.91
0.856
146.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
2.76
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
3
L
3
K
1
M
0
F
1
P
1
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 3 K: 3 M: 1 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
18 reviewed residue count
C95H160N24O20S1 sequence-only estimate (linear, free termini)
1990.52 sequence-only estimate (linear, free termini)
10.84 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
-0.91 sequence-only estimate (linear, free termini)
0.856 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
162.5 µM
Hemolytic Cytotoxic
50% Hemolysis | 162.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of a novel antimicrobial peptide isolated from the venom of solitary bee Colletes daviesanus with phospholipid vesicles and Escherichia coli cells. | J Pept Sci | 2014