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Peptide record

TPDB08690

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08690
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KEFKRIVQRIKDFLRNLV
Physicochemical Analysis
C106H180N32O25
ACGHMPSTWY
RK
2302.79
11.46
6
2
8
+4
5.79
-0.478
118.89
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
3
R
1
N
1
D
0
C
1
E
1
Q
0
G
0
H
2
I
2
L
3
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 2 L: 2 K: 3 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C106H180N32O25
2302.79
11.46
+4
5.79
-0.478
Evidence Records 1 records
Evidence 1 Activity

Activity

1.17±0.18% Hemolysis
Toxicity
175 µg/mL
Hemolytic Cytotoxic
1.17±0.18% Hemolysis | 175 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The Naturally Occurring Host Defense Peptide, LL-37, and Its Truncated Mimetics KE-18 and KR-12 Have Selected Biocidal and Antibiofilm Activities Against Candida albicans, Staphylococcus aureus, and Escherichia coli In vitro. | Front Microbiol | 2017