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Peptide record

TPDB08685

Antibacterial Antifungal Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08685
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GLLKKLLKIAAKVGKKLL
Physicochemical Analysis
C93H176N24O19
RNDCEQHMFPSTWY
LK
1934.57
11.21
6
0
10
+6
2.02
0.606
178.89
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
6
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 6 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C93H176N24O19
1934.57
11.21
+6
2.02
0.606
Evidence Records 4 records
Evidence 1 Activity

Activity

LC50
Hemolysis
25 µM
[Ref.18554256]Hemolysis against human erythrocytes (LC50=25 µM).

Target

human erythrocytes

Source & Reference

Hemolytik PD_Hemolysis
DRAMP4
Chem Biol Drug Des. 2008 Jul 72(1):58-64.

Other

Source Activity Label Source Definition
Hemolysis
Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
50% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7. | Chem Biol Drug Des | 2008
Evidence 3 Activity

Activity

LC50
Toxicity
25 µM
Hemolytic
Hemolytic_activity: [Ref.18554256]Hemolysis against human erythrocytes (LC50=25 µM).

Target

erythrocytes

Source & Reference

NA
DRAMP
Chem Biol Drug Des. 2008 Jul 72(1):58-64.
Evidence 4 Hemolysis

Activity

25 µM
LC50
[Ref.18554256]Hemolysis against human erythrocytes (LC50=25 µM).
Hemolysis

Target

human erythrocytes

Source & Reference

HemoPI PD_Hemolysis
Chem Biol Drug Des. 2008 Jul 72(1):58-64.
DRAMP4
PD_Hemolysis