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Peptide record

TPDB08682

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08682
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb AI4AVP dbAMP 3.0 APD_complete HemoPI Hemolytic2
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RGGRLCYCRPRFCVCVGR
Physicochemical Analysis
C87H145N33O20S4
ANDEQHIKMSTW
R
2101.56
9.95
5
0
5
+5
1.08
-0.089
53.89
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1740
82.80
5
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
0
E
0
Q
3
G
0
H
0
I
1
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
18
C87H145N33O20S4
2101.56
9.95
+5
1.08
-0.089
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
More active against a mprF mutant strain ( Peschel et al., 2001 ). Active against C. albicans ( Cho Y et al., 1998 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
More active against a mprF mutant strain ( Peschel et al., 2001 ). Active against C. albicans ( Cho Y et al., 1998 ).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
More active against a mprF mutant strain ( Peschel et al., 2001 ). Active against C. albicans ( Cho Y et al., 1998 ).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
More active against a mprF mutant strain ( Peschel et al., 2001 ). Active against C. albicans ( Cho Y et al., 1998 ).
Evidence 5 Hemolysis

Source & Reference

APD_complete HemoPI
APD_complete

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.