Peptide record

TPDB08675

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08675
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
WYSEMKRNVQRLERAIEE
Physicochemical Analysis
C101H161N31O31S1
DCGHFPT
E
2337.64
7.17
4
4
7
+0
8.64
-1.400
65.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
299.02
4
Residue Composition
number
1
A
3
R
1
N
0
D
0
C
4
E
1
Q
0
G
0
H
1
I
1
L
1
K
1
M
0
F
0
P
1
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 0 E: 4 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 1 M: 1 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
18
C101H161N31O31S1
2337.64
7.17
+0
8.64
-1.400
Evidence Records 2 records
Evidence 1 Activity

Activity

18% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
18% Hemolysis | 10 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha-helices in proteins: results from analysis of protein structures. | Proteins | 2005
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis