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Peptide record

TPDB08673

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08673
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLRRLRKKIGEIFKKYG
Physicochemical Analysis
C101H175N31O22
ANDCQHMPSTWV
K
2175.69
11.55
7
1
7
+6
4.07
-0.661
108.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
68.48
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
1
E
0
Q
3
G
0
H
2
I
3
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 2 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
18
C101H175N31O22
2175.69
11.55
+6
4.07
-0.661
Evidence Records 2 records
Evidence 1 Activity

Activity

<20% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<20% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. | Eur J Biochem | 1997
Evidence 2 Activity

Activity

<=50% Cell death
Toxicity
100 µM
Cytotoxic
<=50% Cell death | 100 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. | Eur J Biochem | 1997