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Peptide record

TPDB08671

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08671
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia SATPdb AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GWKKWFTKGERLSQRHFA
Physicochemical Analysis
C106H156N32O24
NDCIMPYV
K
2262.60
11.56
6
1
6
+4
1.75
-1.322
27.22
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
486.17
3
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
1
E
1
Q
2
G
1
H
0
I
1
L
3
K
0
M
2
F
0
P
1
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 2 H: 1 I: 0 L: 1 K: 3 M: 0 F: 2 P: 0 S: 1 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
18
C106H156N32O24
2262.60
11.56
+4
1.75
-1.322
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. | Dis Model Mech | 2011
Evidence 2 Activity

Activity

0% Killing
Toxicity
25 µM
Cytotoxic
0% Killing | 25 | µM | target cell: Zebrafish embryos

Target

Zebrafish embryos

Source & Reference

NA
DBAASP
The zebrafish embryo as a tool for screening and characterizing pleurocidin host-defense peptides as anti-cancer agents. | Dis Model Mech | 2011
Evidence 3 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.