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Peptide record

TPDB08669

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08669
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AAKKGCWTVSIPPKPCF
Physicochemical Analysis
C85H133N21O20S2
RNDEQHLMY
KP
1833.24
9.80
3
0
6
+3
0.56
0.047
51.76
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5625
306.83
4
Residue Composition
number
2
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
1
I
0
L
3
K
0
M
1
F
3
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 3 M: 0 F: 1 P: 3 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
17
C85H133N21O20S2
1833.24
9.80
+3
0.56
0.047
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>1000 µM
Hemolytic Cytotoxic
50% Hemolysis | >1000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Selection and redesign for high selectivity of membrane-active antimicrobial peptides from a dedicated sequence/function database. | Biochim Biophys Acta | 2019