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Peptide record

TPDB08652

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08652
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KWCFRVCRRGICYRRCR
Physicochemical Analysis
C96H157N37O19S4
ANDEQHLMPST
R
2261.78
11.13
7
0
5
+7
0.74
-0.706
40.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
7240
320.10
5
Residue Composition
number
0
A
6
R
0
N
0
D
4
C
0
E
0
Q
1
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
17
C96H157N37O19S4
2261.78
11.13
+7
0.74
-0.706
Evidence Records 2 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
195 µM
Hemolytic Cytotoxic
2% Hemolysis | 195 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved strategy for recombinant production and purification of antimicrobial peptide tachyplesin I and its analogs with high cell selectivity. | Biotechnol Appl Biochem | 2017
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.26549611] MHC2=195 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biotechnol Appl Biochem. 2017 Jan 64(1):35-42. doi: 10.1002/bab.1456.