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Peptide record

TPDB08640

Antibacterial Anticancer Antifungal Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08640
Antibacterial Anticancer Antifungal Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSLIPSLVGGSISAFK
Physicochemical Analysis
C83H134N18O22
RNDCEQHMTWY
S
1736.08
10.10
1
0
9
+1
-2.68
1.324
137.65
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
1
K
0
M
2
F
1
P
4
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 1 M: 0 F: 2 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C83H134N18O22
1736.08
10.10
+1
-2.68
1.324
Evidence Records 2 records
Evidence 1 Activity

Activity

6% Hemolysis
Toxicity
160 µM
Hemolytic Cytotoxic
6% Hemolysis | 160 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities. | Biochimie | 2013
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.23770440] 0% hemolysis at 40 µM , 2% hemolysis at 80 µM , 5% hemolysis at 120 µM , 7% hemolysis at 160 µM against horse red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochimie. 2013 Jun 14. doi: 10.1016/j.biochi.2013.06.003.