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Peptide record

TPDB08625

Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08625
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FSGGNCRGFRRRCFCTK
Physicochemical Analysis
C83H131N31O21S3
ADEQHILMPWYV
R
1995.33
11.16
5
0
3
+5
0.84
-0.718
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
6.26
6
Residue Composition
number
0
A
4
R
1
N
0
D
3
C
0
E
0
Q
3
G
0
H
0
I
0
L
1
K
0
M
3
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 3 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 1 M: 0 F: 3 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C83H131N31O21S3
1995.33
11.16
+5
0.84
-0.718
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
270 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 270 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel synthetic peptide from a tomato defensin exhibits antibacterial activities against Helicobacter pylori. | J Pept Sci | 2012
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel synthetic peptide from a tomato defensin exhibits antibacterial activities against Helicobacter pylori. | J Pept Sci | 2012
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic
Hemolytic_activity: [Ref.23124812]<5% hemolysis at 50 µg/mL against mouse red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Sci. 2012 Dec 18(12):755-62.