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Peptide record

TPDB08617

Antibacterial Antifungal standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08617
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 17-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GFGSVLGKALKFGANLL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C80H130N20O20
RDCEQHIMPTWY
GL
1692.03
10.60
2
0
9
+2
-0.94
0.876
120.59
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
4
L
2
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 4 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17 reviewed residue count
C80H130N20O20 sequence-only estimate (linear, free termini)
1692.03 sequence-only estimate (linear, free termini)
10.60 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
-0.94 sequence-only estimate (linear, free termini)
0.876 sequence-only estimate (linear, free termini)
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against S. aureus (MIC 12.5 uM) and E. coli (MIC 50 uM). Reg. 12/2014.
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against S. aureus (MIC 12.5 uM) and E. coli (MIC 50 uM). Reg. 12/2014.
Evidence 3 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

Active against S. aureus (MIC 12.5 uM) and E. coli (MIC 50 uM). Reg. 12/2014.
Evidence 4 Activity

Activity

MIC
Antifungal
50 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active against S. aureus (MIC 12.5 uM) and E. coli (MIC 50 uM). Reg. 12/2014.