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Peptide record

TPDB08616

Antibacterial Antifungal Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08616
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPLLVGAISSILPKIF
Physicochemical Analysis
C92H150N18O20
RNDCEQHMTWY
L
1828.31
10.10
1
0
11
+1
-3.37
1.835
183.53
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
4
L
1
K
0
M
2
F
2
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 4 K: 1 M: 0 F: 2 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C92H150N18O20
1828.31
10.10
+1
-3.37
1.835
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.faecium 091299

Source & Reference

dbAMP

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 4 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

eus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP

Other

>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC>100 uM), and fungi C.glabrata 090902 (MIC>100 uM), and C.albicans(AT
Evidence 7 Activity

Activity

MIC
Antibacterial
>100 µM

Target

P.faecalis X29

Source & Reference

dbAMP

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC>100 uM), and fungi C.glabrata 090902 (MIC>100 uM), and C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
>100 µM

Target

C.glabrata 090902

Source & Reference

dbAMP

Other

57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC>100 uM), and fungi C.glabrata 090902 (MIC>100 uM), and C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.
Evidence 10 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.faecium 091299

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC
Evidence 11 Activity

Activity

MIC
Antifungal
>100 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumo
Evidence 12 Activity

Activity

MIC
Antifungal
6.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

eus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (MIC>100 uM), E.faecalis 981 (MIC>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloa
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µM

Target

K.pneumoniae 08040724

Source & Reference

dbAMP CAFPdb Antifungipept

Other

>100 uM), N. asteroides 201118 (MIC 6.3 uM), Gram- P.aeruginosa CGMCC 1.50 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC
Evidence 14 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0 (MIC >100 uM), K.pneumoniae 08040724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC>100 uM), and fungi C.glabrata 090902 (MIC>100 uM), and C.albicans(AT
Evidence 15 Activity

Activity

MIC
Antifungal
>100 µM

Target

P.faecalis X29

Source & Reference

dbAMP CAFPdb Antifungipept

Other

40724 (MIC >100 uM), E.cloacae CGMCC 1.57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC>100 uM), and fungi C.glabrata 090902 (MIC>100 uM), and C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 16 Activity

Activity

MIC
Antifungal
>100 µM

Target

C.glabrata 090902

Source & Reference

dbAMP CAFPdb Antifungipept

Other

57 (MIC >100 uM), E.coli ATCC 25922 (MIC >100 uM), P.faecalis X29 (MIC>100 uM), and fungi C.glabrata 090902 (MIC>100 uM), and C.albicans(ATCC 10231 (MIC>100 uM).
Evidence 17 Activity

Activity

12% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
12% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 18 Activity

Activity

26% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
26% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 19 Activity

Activity

41% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
41% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 20 Activity

Activity

59% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
59% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 21 Activity

Activity

75% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
75% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 22 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.