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Peptide record

TPDB08605

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08605
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RPRCWIKIKFRCKSLKF
Physicochemical Analysis
C103H169N31O19S2
ANDEQGHMTYV
K
2209.79
11.53
7
0
6
+7
1.20
-0.529
68.82
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5625
254.55
3
Residue Composition
number
0
A
3
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
1
L
4
K
0
M
2
F
1
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 2 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C103H169N31O19S2
2209.79
11.53
+7
1.20
-0.529
Evidence Records 12 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli, P. aeruginosa, S. aureus, and fungus C. albicans. Also exerted strong nematocidal activities against C. elegans.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli, P. aeruginosa, S. aureus, and fungus C. albicans. Also exerted strong nematocidal activities against C. elegans.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against E. coli, P. aeruginosa, S. aureus, and fungus C. albicans. Also exerted strong nematocidal activities against C. elegans.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against E. coli, P. aeruginosa, S. aureus, and fungus C. albicans. Also exerted strong nematocidal activities against C. elegans.
Evidence 5 Activity

Activity

1% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. | J Pept Sci | 2011
Evidence 6 Activity

Activity

5% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. | J Pept Sci | 2011
Evidence 7 Activity

Activity

11% Hemolysis
Toxicity
1000 µg/mL
Hemolytic Cytotoxic
11% Hemolysis | 1000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. | J Pept Sci | 2011
Evidence 8 Activity

Activity

2% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. | J Pept Sci | 2011
Evidence 9 Activity

Activity

5% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 250 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. | J Pept Sci | 2011
Evidence 10 Activity

Activity

12% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 500 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. | J Pept Sci | 2011
Evidence 11 Activity

Activity

66% Hemolysis
Toxicity
1000 µg/mL
Hemolytic Cytotoxic
66% Hemolysis | 1000 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. | J Pept Sci | 2011
Evidence 12 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.21644248] At the concentration of 0.0625 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.6% & 2.2% At the concentration of 0.125 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.8% & 4.7% At the concentration of 0.25 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 5.2%&5.2% At the concentration of 0.5 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 5.3% & 12.4% At the concentration of 1 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 11.3% & 66.3%.

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Sci. 2011 Sep 17(9):627-631.