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Peptide record

TPDB08593

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08593
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab AFP-GFuse Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLGMIPKLIKKLIKAFK
Physicochemical Analysis
C99H170N22O18S1
RNDCEQHSTWYV
K
1988.64
11.12
5
0
10
+5
0.14
0.747
143.53
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
3
L
5
K
1
M
2
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 3 K: 5 M: 1 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C99H170N22O18S1
1988.64
11.12
+5
0.14
0.747
Evidence Records 4 records
Evidence 1 Activity

Activity

28% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
28% Hemolysis | 5 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities. | Biochimie | 2013
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
100% Hemolysis | 20 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities. | Biochimie | 2013
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
30 %
Hemolytic
Hemolytic_activity: [Ref.23770440] 30% hemolysis at 5 µM , 85% hemolysis at 10 µM , 100% hemolysis at 20 µM against horse red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochimie. 2013 Sep 95(9):1784-94. doi: 10.1016/j.biochi.2013.06.003.
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis