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Peptide record

TPDB08582

Antibacterial Antifungal standard
17 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08582
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RGGLCYCRGRFCVCVGR
Physicochemical Analysis
C78H129N29O19S4
ANDEQHIKMPSTW
RCG
1905.31
9.27
4
0
5
+4
-0.17
0.241
57.06
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1740
91.32
5
Residue Composition
number
0
A
4
R
0
N
0
D
4
C
0
E
0
Q
4
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
17
C78H129N29O19S4
1905.31
9.27
+4
-0.17
0.241
Evidence Records 30 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.5 µM

Target

Escherichia coli ATCC 25922 or ML35p or BW 25113

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli ATCC 25922 or ML35p or BW 25113 (MIC 0.5 uM), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K
Evidence 2 Activity

Activity

MIC
Antibacterial
2-8 µM

Target

Pseudomonas aeruginosa PAO1 or ATCC 27853 or ATCC 9027

Source & Reference

dbAMP

Other

active against E. coli ATCC 25922 or ML35p or BW 25113 (MIC 0.5 uM), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC
Evidence 3 Activity

Activity

MIC
Antibacterial
0.5 µM

Target

A. baumannii

Source & Reference

dbAMP

Other

35p or BW 25113 (MIC 0.5 uM), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM),
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µM

Target

Klebsiella pneumoniae ATCC 700603

Source & Reference

dbAMP

Other

), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Al
Evidence 5 Activity

Activity

MIC
Antibacterial
2-4 µM

Target

Staphylococcus aureus 209P or ATCC 29213 or MRSA

Source & Reference

dbAMP

Other

ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC
Evidence 6 Activity

Activity

MIC
Antibacterial
0.5 µM

Target

M. luteus B-1314

Source & Reference

dbAMP

Other

pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATC
Evidence 7 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP

Other

MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25
Evidence 8 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP

Other

14 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATC
Evidence 9 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

R. equi ATCC 6939

Source & Reference

dbAMP

Other

Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. c
Evidence 10 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aer
Evidence 11 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Staphylococcus epidermidis ATCC 14990

Source & Reference

dbAMP

Other

9212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi
Evidence 12 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C
Evidence 13 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP

Other

ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C.albicans ATCC 10231 (MIC 256 ug/ml) ( Ro
Evidence 14 Activity

Activity

MIC
Antibacterial
256 µg/mL

Target

A.niger ATCC 16404

Source & Reference

dbAMP

Other

, Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C.albicans ATCC 10231 (MIC 256 ug/ml) ( Rodziewicz-Motowidlo et al., 2010 ).
Evidence 15 Activity

Activity

MIC
Antibacterial
256 µg/mL

Target

C.albicans ATCC 10231

Source & Reference

dbAMP

Other

), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C.albicans ATCC 10231 (MIC 256 ug/ml) ( Rodziewicz-Motowidlo et al., 2010 ).
Evidence 16 Activity

Activity

MIC
Antifungal
0.5 µM

Target

Escherichia coli ATCC 25922 or ML35p or BW 25113

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli ATCC 25922 or ML35p or BW 25113 (MIC 0.5 uM), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K
Evidence 17 Activity

Activity

MIC
Antifungal
2-8 µM

Target

Pseudomonas aeruginosa PAO1 or ATCC 27853 or ATCC 9027

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against E. coli ATCC 25922 or ML35p or BW 25113 (MIC 0.5 uM), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC
Evidence 18 Activity

Activity

MIC
Antifungal
0.5 µM

Target

A. baumannii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

35p or BW 25113 (MIC 0.5 uM), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM),
Evidence 19 Activity

Activity

MIC
Antifungal
4 µM

Target

Klebsiella pneumoniae ATCC 700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), P. aeruginosa PAO1 or ATCC 27853 or ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Al
Evidence 20 Activity

Activity

MIC
Antifungal
2-4 µM

Target

Staphylococcus aureus 209P or ATCC 29213 or MRSA

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ATCC 9027 (MIC 2-8 uM), A. baumannii (MIC 0.5 uM), K. pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC
Evidence 21 Activity

Activity

MIC
Antifungal
0.5 µM

Target

M. luteus B-1314

Source & Reference

dbAMP CAFPdb Antifungipept

Other

pneumoniae ATCC 700603 (MIC 4 uM), S. aureus 209P or ATCC 29213 or MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATC
Evidence 22 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MRSA (MIC 2-4 uM), and M. luteus B-1314 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25
Evidence 23 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

14 (MIC 0.5 uM). Also, active against Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATC
Evidence 24 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

R. equi ATCC 6939

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Gram+ bacteria B. subtilis ATCC 6633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. c
Evidence 25 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

633 (MIC 8 ug/ml), E. faecalis ATCC 29212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aer
Evidence 26 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Staphylococcus epidermidis ATCC 14990

Source & Reference

dbAMP CAFPdb Antifungipept

Other

9212 (MIC 8 ug/ml), R. equi ATCC 6939 (MIC 8 ug/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi
Evidence 27 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

/ml), S. aureus ATCC 25923 (MIC 32 ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C
Evidence 28 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), S. epidermidis ATCC 14990 (MIC 4 ug/ml), Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C.albicans ATCC 10231 (MIC 256 ug/ml) ( Ro
Evidence 29 Activity

Activity

MIC
Antifungal
256 µg/mL

Target

A.niger ATCC 16404

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, Gram- E. coli ATCC 25922 (MIC 16 ug/ml), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C.albicans ATCC 10231 (MIC 256 ug/ml) ( Rodziewicz-Motowidlo et al., 2010 ).
Evidence 30 Activity

Activity

MIC
Antifungal
256 µg/mL

Target

C.albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), P. aeruginosa ATCC 27853 (MIC 32 ug/ml), fungi A.niger ATCC 16404 (MIC 256 ug/ml), and C.albicans ATCC 10231 (MIC 256 ug/ml) ( Rodziewicz-Motowidlo et al., 2010 ).