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Peptide record

TPDB08579

Antibacterial Anticancer Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08579
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia CancerPPD 2.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
NGVQPKYRWWRWWRRWW
Physicochemical Analysis
C126H164N38O21
ADCEHILMFST
W
2546.93
12.41
5
0
8
+5
-6.28
-1.965
17.06
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
34490
1354.18
3
Residue Composition
number
0
A
4
R
1
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
0
S
0
T
6
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 6 Y: 1 V: 1
Chemical Descriptors
17
C126H164N38O21
2546.93
12.41
+5
-6.28
-1.965
Evidence Records 5 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
44 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 44 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving the antibacterial activity and selectivity of an ultra short peptide by hydrophobic and hydrophilic amino acid stretches. | Bioorg Med Chem Lett | 2013
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Cationic Antimicrobial Peptides Derived from Crocodylus siamensis Leukocyte Extract, Revealing Anticancer Activity and Apoptotic Induction on Human Cervical Cancer Cells. | Protein J | 2016
Evidence 3 Activity

Activity

<5% Hemolysis
Toxicity
23 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 23 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving the antibacterial activity and selectivity of an ultra short peptide by hydrophobic and hydrophilic amino acid stretches. | Bioorg Med Chem Lett | 2013
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Environ Toxicol Pharmacol. 2018 Sep 62:164-176.
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis