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Peptide record

TPDB08559

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08559
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
EWFKARRWGWRMKKLQA
Physicochemical Analysis
C107H161N33O21S1
NDCHIPSTYV
RKW
2277.72
12.14
6
1
8
+5
0.20
-1.365
34.71
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
16500
724.41
1
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
1
E
1
Q
1
G
0
H
0
I
1
L
3
K
1
M
1
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 3 M: 1 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
17
C107H161N33O21S1
2277.72
12.14
+5
0.20
-1.365
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
2% Hemolysis | 400 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Designed low amphipathic peptides with alpha-helical propensity exhibiting antimicrobial activity via a lipid domain formation mechanism. | Peptides | 2010