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Peptide record

TPDB08547

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08547
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KFWKLLKKALRLWAKVL
Physicochemical Analysis
C108H177N27O18
NDCEQGHIMPSTY
LK
2141.76
11.85
6
0
11
+6
-2.14
0.224
143.53
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
513.60
0
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
5
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
17
C108H177N27O18
2141.76
11.85
+6
-2.14
0.224
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide CPF-C1 Analogs with Superior Stabilities and Activities against Multidrug-Resistant Bacteria. | Chem Biol Drug Des | 2017
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.28371431] 0% hemolysis at 256 µg/ml , 5% hemolysis at 512 µg/ml against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Chem Biol Drug Des. 2017 Nov 90(5):690-702. doi: 10.1111/cbdd.12988.