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Peptide record

TPDB08543

Antibacterial Antifungal Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08543
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP PD_Hemolysis ToxinPred 3.0
standard
No
A 17-aa standard-residue multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ILGPVLGLVGSALGGLI
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C73H129N17O19
RNDCEQHKMFTWY
GL
1548.93
6.02
0
0
10
-0
-2.68
1.988
200.59
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
2
I
5
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 2 L: 5 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
17 reviewed residue count
C73H129N17O19 sequence-only estimate (linear, free termini)
1548.93 sequence-only estimate (linear, free termini)
6.02 sequence-only estimate (linear, free termini)
-0 sequence-only estimate (linear, free termini)
-2.68 sequence-only estimate (linear, free termini)
1.988 sequence-only estimate (linear, free termini)
Evidence Records 5 records
Evidence 1 Activity

Activity

65% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
65% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 2 Activity

Activity

60% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
60% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 3 Activity

Activity

37% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
37% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 4 Activity

Activity

1% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis