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Peptide record

TPDB08535

Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08535
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GKEFKRIVKWPWWPWRR
Physicochemical Analysis
C117H167N33O20
ANDCQHLMSTY
W
2355.82
12.14
6
1
7
+5
-0.44
-1.435
40.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
22000
933.86
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
1
I
0
L
3
K
0
M
1
F
2
P
0
S
0
T
4
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 3 M: 0 F: 1 P: 2 S: 0 T: 0 W: 4 Y: 0 V: 1
Chemical Descriptors
17
C117H167N33O20
2355.82
12.14
+5
-0.44
-1.435
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
5% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of bactericidal efficiency, cell selectivity, and mechanism of short interspecific hybrid peptides. | Amino Acids | 2018
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 5%Hemolysis>128 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2018 Apr 50(3-4):453-468.