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Peptide record

TPDB08533

Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08533
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GFWSSVWDGAKNVGTAI
Physicochemical Analysis
C83H119N21O24
RCEQHLMPY
G
1794.98
6.75
1
1
8
-0
-2.27
0.182
68.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
612.82
4
Residue Composition
number
2
A
0
R
1
N
1
D
0
C
0
E
0
Q
3
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
2
S
1
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 2 T: 1 W: 2 Y: 0 V: 2
Chemical Descriptors
17
C83H119N21O24
1794.98
6.75
-0
-2.27
0.182
Evidence Records 3 records
Evidence 1 Activity

Activity

60% Killing
Toxicity
32 µM
Cytotoxic
60% Killing | 32 | µM | target cell: Human embryonic fibroblasts

Target

Human embryonic fibroblasts

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain. | Mar Drugs | 2018
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
1% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain. | Mar Drugs | 2018
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Mar Drugs. 2018 Oct 23 16(11):401.