Back to search

Peptide record

TPDB08532

Antibacterial Antifungal Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08532
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFWGKLWEGVKNAIKKK
Physicochemical Analysis
C96H149N25O21
RDCQHMPSTY
K
1989.39
10.71
5
1
7
+4
1.62
-0.729
68.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
552.93
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
1
E
0
Q
3
G
0
H
1
I
1
L
5
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 1 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
17
C96H149N25O21
1989.39
10.71
+4
1.62
-0.729
Evidence Records 5 records
Evidence 1 Activity

Activity

EC50
Toxicity
17.81 µM
Cytotoxic
EC50 | 17.81 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
39.76 µM
Hemolytic Cytotoxic
10% Hemolysis | 39.76 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
1110 µM
Hemolytic Cytotoxic
50% Hemolysis | 1110 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 4 Activity

Activity

90% Hemolysis
Toxicity
30984.53 µM
Hemolytic Cytotoxic
90% Hemolysis | 30984.53 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis