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Peptide record

TPDB08527

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08527
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FSGGDCRGLRRRCFCTR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C80H132N32O22S3
ANEQHIKMPWYV
R
1990.31
10.71
5
1
3
+4
4.22
-0.694
22.94
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
0.06
5
Residue Composition
number
0
A
5
R
0
N
1
D
3
C
0
E
0
Q
3
G
0
H
0
I
1
L
0
K
0
M
2
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 1 C: 3 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 0 F: 2 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
17 reviewed residue count
C80H132N32O22S3 sequence-only estimate (linear, free termini)
1990.31 sequence-only estimate (linear, free termini)
10.71 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
4.22 sequence-only estimate (linear, free termini)
-0.694 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Toxicity
140.76 µM
Cytotoxic
IC50 | 140.76 | µM | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
Structural and biological features of a novel plant defensin from Brugmansia x candida. | PLoS One | 2018