Back to search

Peptide record

TPDB08525

Anti-inflammatory Antibacterial Antifungal Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08525
Anti-inflammatory Antibacterial Antifungal Toxicity
Anti-infective peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia AntiBP3 AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 17-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiBP3, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
MKTFLRLYRSLINKVLH
Physicochemical Analysis
C99H166N28O22S1
ADCEQGPW
L
2132.64
11.51
5
0
9
+4
0.47
0.135
131.76
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
69.87
4
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
4
L
2
K
1
M
1
F
0
P
1
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 4 K: 2 M: 1 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
17
C99H166N28O22S1
2132.64
11.51
+4
0.47
0.135
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 11775 (MIC 4 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 4 ug/ml). Note that
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Active against E. coli ATCC 11775 (MIC 4 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 4 ug/ml). Note that the mature sequence may differ from
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

Active against E. coli ATCC 11775 (MIC 4 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 4 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 4 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 11775 (MIC 4 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 4 ug/ml). Note that
Evidence 5 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 11775 (MIC 4 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 4 ug/ml). Note that the mature sequence may differ from
Evidence 6 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 11775 (MIC 4 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 4 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016
Evidence 8 Activity

Activity

10% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 100 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016
Evidence 9 Activity

Activity

30% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
30% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016