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Peptide record

TPDB08516

Antibacterial Antifungal Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08516
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LLGPVLGLVSNVLGGLL
Physicochemical Analysis
C77H136N18O20
ARDCEQHIKMFTWY
L
1634.04
6.02
0
0
10
-0
-2.67
1.865
211.76
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
7
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 7 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
17
C77H136N18O20
1634.04
6.02
-0
-2.67
1.865
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>512 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >512 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
The synergistic antimicrobial effects of novel bombinin and bombinin H peptides from the skin secretion of Bombina orientalis | Biosci Rep | 2017
Evidence 2 Activity

Activity

50% Cell death
Toxicity
103.51±0.43 µM
Cytotoxic
50% Cell death | 103.51±0.43 | µM | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
The synergistic antimicrobial effects of novel bombinin and bombinin H peptides from the skin secretion of Bombina orientalis | Biosci Rep | 2017