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Peptide record

TPDB08495

Antibacterial Antifungal Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08495
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KPYLKRFQVYYKGRMWC
Physicochemical Analysis
C108H160N28O22S2
ANDEHIST
KY
2266.75
10.34
5
0
8
+5
-1.13
-0.929
40.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
9970
439.84
5
Residue Composition
number
0
A
2
R
0
N
0
D
1
C
0
E
1
Q
1
G
0
H
0
I
1
L
3
K
1
M
1
F
1
P
0
S
0
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 3 M: 1 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 3 V: 1
Chemical Descriptors
17
C108H160N28O22S2
2266.75
10.34
+5
-1.13
-0.929
Evidence Records 8 records
Evidence 1 Activity

Activity

22% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
22% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005
Evidence 2 Activity

Activity

20% Hemolysis
Toxicity
125 µM
Hemolytic Cytotoxic
20% Hemolysis | 125 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005
Evidence 3 Activity

Activity

9% Hemolysis
Toxicity
62.5 µM
Hemolytic Cytotoxic
9% Hemolysis | 62.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005
Evidence 4 Activity

Activity

8% Hemolysis
Toxicity
31.3 µM
Hemolytic Cytotoxic
8% Hemolysis | 31.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005
Evidence 5 Activity

Activity

7% Hemolysis
Toxicity
15.6 µM
Hemolytic Cytotoxic
7% Hemolysis | 15.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005
Evidence 6 Activity

Activity

6% Hemolysis
Toxicity
7.8 µM
Hemolytic Cytotoxic
6% Hemolysis | 7.8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005
Evidence 7 Activity

Activity

4% Hemolysis
Toxicity
3.9 µM
Hemolytic Cytotoxic
4% Hemolysis | 3.9 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005
Evidence 8 Activity

Activity

0% Hemolysis
Toxicity
1.95 µM
Hemolytic Cytotoxic
0% Hemolysis | 1.95 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. | Dev Comp Immunol | 2005