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Peptide record

TPDB08494

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08494
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KNKRKRRRRRRGGRRRR
Physicochemical Analysis
C92H182N54O19
ADCEQHILMFPSTWYV
R
2348.81
13.40
14
0
0
+14
12.32
-3.853
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
11
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 11 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C92H182N54O19
2348.81
13.40
+14
12.32
-3.853
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
16.50 µM
Hemolytic Cytotoxic
0% Hemolysis | 16.50 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Mode of action of the antimicrobial peptide Mel4 is independent of Staphylococcus aureus cell membrane permeability. | PLoS One | 2019
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
1703.68 µM
Hemolytic Cytotoxic
5% Hemolysis | 1703.68 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Mode of action of the antimicrobial peptide Mel4 is independent of Staphylococcus aureus cell membrane permeability. | PLoS One | 2019