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Peptide record

TPDB08472

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08472
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RWCVRARVRGVRYRRCW
Physicochemical Analysis
C99H160N40O19S2
NDEQHILKMFPST
R
2278.74
12.28
7
0
7
+7
0.60
-0.918
57.06
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12615
553.60
3
Residue Composition
number
1
A
7
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 3
Chemical Descriptors
17
C99H160N40O19S2
2278.74
12.28
+7
0.60
-0.918
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
88 µM
Hemolytic Cytotoxic
10% Hemolysis | 88 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Bioengineering and functional characterization of arenicin shortened analogs with enhanced antibacterial activity and cell selectivity. | J Pept Sci | 2016