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Peptide record

TPDB08465

Antibacterial Antifungal Antiparasitic Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08465
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP dbAMP 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
NLLNKALGTVNGLLGRS
Physicochemical Analysis
C75H134N24O23
DCEQHIMFPWY
L
1740.04
11.49
2
0
7
+2
0.46
0.200
137.65
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
1
R
3
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
5
L
1
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 5 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C75H134N24O23
1740.04
11.49
+2
0.46
0.200
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
50% Hemolysis | >256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Dendropsophin 1, a novel antimicrobial peptide from the skin secretion of the endemic Colombian frog Dendropsophus columbianus. | Nat Prod Res | 2017
Evidence 2 Activity

Activity

IC50
Toxicity
105±14 µM
Cytotoxic
IC50 | 105±14 | µM | target cell: Rat myoblast L6 cells

Target

Rat myoblast L6 cells

Source & Reference

NA
DBAASP
Dendropsophin 1, a novel antimicrobial peptide from the skin secretion of the endemic Colombian frog Dendropsophus columbianus. | Nat Prod Res | 2017