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Peptide record

TPDB08453

Antibacterial Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08453
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GGHKLAKLAKKLAKLAK
Physicochemical Analysis
C82H151N25O18
RNDCEQIMFPSTWYV
K
1775.26
11.21
7
0
8
+6
4.00
-0.294
115.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
4
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 4 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C82H151N25O18
1775.26
11.21
+6
4.00
-0.294
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
4 µM
Hemolytic Cytotoxic
10% Hemolysis | 4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved bioactivity of antimicrobial peptides by addition of amino-terminal copper and nickel (ATCUN) binding motifs. | ChemMedChem | 2014
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis