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Peptide record

TPDB08441

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08441
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KNWKKIASIGKEVLKAL
Physicochemical Analysis
C90H156N24O22
RDCQHMFPTY
K
1926.38
10.71
5
1
8
+4
3.67
-0.247
120.59
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
285.51
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
0
Q
1
G
0
H
2
I
2
L
5
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 5 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
17
C90H156N24O22
1926.38
10.71
+4
3.67
-0.247
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >>100 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs | Peptides | 2008