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Peptide record

TPDB08433

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08433
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLGSVLGKALKIGANLL
Physicochemical Analysis
C74H134N20O20
RDCEQHMFPTWY
L
1624.00
10.60
2
0
9
+2
-0.81
1.035
166.47
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
5
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 5 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C74H134N20O20
1624.00
10.60
+2
-0.81
1.035
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
50% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human oral fibroblasts

Target

Human oral fibroblasts

Source & Reference

NA
DBAASP
Antimicrobial and immunomodulatory properties of PGLa-AM1, CPF-AM1, and magainin-AM1: potent activity against oral pathogens. | Regul Pept | 2014
Evidence 3 Activity

Activity

LC50
Toxicity
200 µM
Hemolytic
Hemolytic_activity: [Ref.20226221] LC50>200µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2010 Jun 31(6):989-94.