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Peptide record

TPDB08431

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08431
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FFSLLPSLIGGLVSAIK
Physicochemical Analysis
C86H140N18O21
RNDCEQHMTWY
L
1762.17
10.10
1
0
10
+1
-3.37
1.594
160.59
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
4
L
1
K
0
M
2
F
1
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 1 M: 0 F: 2 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C86H140N18O21
1762.17
10.10
+1
-3.37
1.594
Evidence Records 4 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Imcroporin, a new cationic antimicrobial peptide from the venom of the scorpion Isometrus maculates. | Antimicrob Agents Chemother | 2009
Evidence 2 Activity

Activity

25% Killing
Toxicity
100 µg/mL
Cytotoxic
25% Killing | 100 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Imcroporin, a new cationic antimicrobial peptide from the venom of the scorpion Isometrus maculates. | Antimicrob Agents Chemother | 2009
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2009 Aug 53(8):3472-7.
Evidence 4 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.