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Peptide record

TPDB08428

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08428
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPVILPVIGKLLSGIL
Physicochemical Analysis
C90H154N18O19
ARNDCEQHMTWY
L
1792.32
10.10
1
0
11
+1
-2.68
2.059
217.65
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
5
L
1
K
0
M
1
F
2
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 5 K: 1 M: 0 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
17
C90H154N18O19
1792.32
10.10
+1
-2.68
2.059
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus (MIC 37.5 uM) but not E.coli (MIC>150 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
>150 µM

Target

E.coli

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus (MIC 37.5 uM) but not E.coli (MIC>150 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
37.5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus (MIC 37.5 uM) but not E.coli (MIC>150 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
>150 µM

Target

E.coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus (MIC 37.5 uM) but not E.coli (MIC>150 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
37.5 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus (MIC 37.5 uM) but not E.coli (MIC>150 uM).
Evidence 6 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

E.coli

Source & Reference

DRAMP

Other

Active against S. aureus (MIC 37.5 uM) but not E.coli (MIC>150 uM).
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
50% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning and sequence analyses of preprotemporin mRNAs containing premature stop codons from extradermal tissues of Rana tagoi. | Peptides | 2006
Evidence 8 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.