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Peptide record

TPDB08398

Antibacterial Antifungal Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08398
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept AI4AVP DRAVP 2.0 ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLVGTLLGHIGKAILGG
Physicochemical Analysis
C72H126N20O19
RNDCEQMFPSWY
G
1575.91
10.10
2
0
8
+1
-0.81
1.176
160.59
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
6
G
1
H
2
I
4
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 6 H: 1 I: 2 L: 4 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C72H126N20O19
1575.91
10.10
+1
-0.81
1.176
Evidence Records 6 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against yellow fever virus (YFV). At 20 ug/ml, a synthetic peptide showed 35% protective effect in Vero E6 cells infected with FYV.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against yellow fever virus (YFV). At 20 ug/ml, a synthetic peptide showed 35% protective effect in Vero E6 cells infected with FYV.
Evidence 3 Activity

Activity

Antiviral

Source & Reference

DRAVP 2.0

Other

Active against yellow fever virus (YFV). At 20 ug/ml, a synthetic peptide showed 35% protective effect in Vero E6 cells infected with FYV.
Evidence 4 Activity

Activity

CC50
Toxicity
>100 µM
Cytotoxic
CC50 | >100 | µM | target cell: Human monocytes

Target

Human monocytes

Source & Reference

NA
DBAASP
Unveiling the Multifaceted Mechanisms of Antibacterial Activity of Buforin II and Frenatin 2.3S Peptides from Skin Micro-Organs of the Orinoco Lime Treefrog (Sphaenorhynchus lacteus). | Int J Mol Sci | 2018
Evidence 5 Activity

Activity

<10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<10% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Unveiling the Multifaceted Mechanisms of Antibacterial Activity of Buforin II and Frenatin 2.3S Peptides from Skin Micro-Organs of the Orinoco Lime Treefrog (Sphaenorhynchus lacteus). | Int J Mol Sci | 2018
Evidence 6 Activity

Activity

37.5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
37.5% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Unveiling the Multifaceted Mechanisms of Antibacterial Activity of Buforin II and Frenatin 2.3S Peptides from Skin Micro-Organs of the Orinoco Lime Treefrog (Sphaenorhynchus lacteus). | Int J Mol Sci | 2018