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Peptide record

TPDB08389

Antibacterial Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB08389
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RRRRRRAAFAAWAAFAA
Physicochemical Analysis
C89H142N36O18
NDCEQGHILKMPSTYV
A
2004.34
13.10
6
0
11
+6
-0.61
-0.465
47.06
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
274.40
0
Residue Composition
number
8
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C89H142N36O18
2004.34
13.10
+6
-0.61
-0.465
Evidence Records 5 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
3% Hemolysis | 200 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
1% Hemolysis | 50 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 3 Activity

Activity

26% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
26% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 4 Activity

Activity

14% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
14% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 5 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis