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Peptide record

TPDB08371

Antibacterial Anticancer Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08371
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LRRLRRRWWRRRLRRL
Physicochemical Analysis
C106H186N48O17
ANDCEQGHIKMFPSTYV
R
2404.95
13.35
10
0
6
+10
2.16
-1.975
97.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
11000
457.39
0
Residue Composition
number
0
A
10
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
16
C106H186N48O17
2404.95
13.35
+10
2.16
-1.975
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Design of Heptad Amphiphiles To Enhance Cell Selectivity, Salt Resistance, Antibiofilm Properties and Their Membrane-Disruptive Mechanism. | J Med Chem | 2017