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Peptide record

TPDB08354

M4 Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08354
M4
Antibacterial Anticancer Antifungal Antiparasitic Cell-penetrating Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb CellPPD CellPPD-MOD CPPsite3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
FQWQRNMRKVRGPPVS-NH2
Physicochemical Analysis
C88H140N30O21S1
ADCEHILTY
R
1986.33
12.71
4
0
5
+4
2.97
-1.256
36.25
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
276.89
4
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
2
Q
1
G
0
H
0
I
0
L
1
K
1
M
1
F
2
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 1 H: 0 I: 0 L: 0 K: 1 M: 1 F: 1 P: 2 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
16
C88H140N30O21S1
1986.33
12.71
+4
2.97
-1.256
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (fluorescein)
Vesicles at low concentartion and cytoplasm and nucleus at high concentart
Lower than hLF peptide
In vitro
CCCTTTCSSSCCSCCC
Additional Detail Fields 1 fields
CCCTTTCSSSCCSCCC