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Peptide record

TPDB08353

Antibacterial Antifungal standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08353
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 16-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FIGKLISAASGLLSHL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C76H127N19O20
RNDCEQMPTWYV
L
1626.96
10.10
2
0
9
+1
-1.10
1.269
158.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
2
I
4
L
1
K
0
M
1
F
0
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 4 K: 1 M: 0 F: 1 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16 reviewed residue count
C76H127N19O20 sequence-only estimate (linear, free termini)
1626.96 sequence-only estimate (linear, free termini)
10.10 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
-1.10 sequence-only estimate (linear, free termini)
1.269 sequence-only estimate (linear, free termini)
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
38.4 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 38.4 uM), S. aureus (MIC 9.5 uM), and C.albicans (MIC 150 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
9.5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 38.4 uM), S. aureus (MIC 9.5 uM), and C.albicans (MIC 150 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
150 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 38.4 uM), S. aureus (MIC 9.5 uM), and C.albicans (MIC 150 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
38.4 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 38.4 uM), S. aureus (MIC 9.5 uM), and C.albicans (MIC 150 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
9.5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 38.4 uM), S. aureus (MIC 9.5 uM), and C.albicans (MIC 150 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
150 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 38.4 uM), S. aureus (MIC 9.5 uM), and C.albicans (MIC 150 uM).