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Peptide record

TPDB08351

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08351
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SFHVFPPWMCKSLKKC
Physicochemical Analysis
C91H136N22O19S3
ARNDEQGITY
K
1938.40
9.80
4
0
6
+3
-0.22
-0.006
42.50
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5625
290.19
4
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
1
H
0
I
1
L
3
K
1
M
2
F
2
P
2
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 3 M: 1 F: 2 P: 2 S: 2 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
16
C91H136N22O19S3
1938.40
9.80
+3
-0.22
-0.006
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
70 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
>160 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
70 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
>160 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
70 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 6 Activity

Activity

MIC
Antiparasitic
>160 µM

Target

C.albicans

Source & Reference

DRAMP

Other

Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 7 Activity

Activity

MIC
Antiviral
70 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 8 Activity

Activity

MIC
Antiviral
>160 µM

Target

C.albicans

Source & Reference

DRAMP

Other

Active against E. coli (MIC 70 uM) but not S.aureus adn C.albicans (MIC >160 uM).
Evidence 9 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Limnonectins: a new class of antimicrobial peptides from the skin secretion of the Fujian large-headed frog (Limnonectes fujianensis). | Biochimie | 2011
Evidence 10 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.21396976] It exhibits no hemolytic activity at a concentration of up to 160 µM.

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochimie. 2011 Jun 93(6):981-987.