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Peptide record

TPDB08350

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08350
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPIAGKLLSGLSGLL
Physicochemical Analysis
C77H131N17O19
RNDCEQHMTWYV
L
1598.99
10.10
1
0
9
+1
-3.24
1.475
176.88
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
6
L
1
K
0
M
1
F
1
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 6 K: 1 M: 0 F: 1 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C77H131N17O19
1598.99
10.10
+1
-3.24
1.475
Evidence Records 3 records
Evidence 1 Activity

Activity

12% Hemolysis
Toxicity
62.54 µM
Hemolytic Cytotoxic
12% Hemolysis | 62.54 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anticancer Activities of Antimicrobial BmKn2 Peptides Against Oral and Colon Cancer Cells | Int J Pept Res Ther | 2014
Evidence 2 Activity

Activity

12% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Five novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis | Comp Biochem Physiol B Biochem Mol Biol | 2010
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:19843479]12% hemolytic activity at 100 µg/mL against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan 155(1):72-76.