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Peptide record

TPDB08349

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08349
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FKVQNQHGQVVKIFHH
Physicochemical Analysis
C90H136N28O21
ARDCELMPSTWY
QHV
1946.25
10.60
5
0
6
+2
4.67
-0.569
78.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
3
Q
1
G
3
H
1
I
0
L
2
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 3 G: 1 H: 3 I: 1 L: 0 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
16
C90H136N28O21
1946.25
10.60
+2
4.67
-0.569
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
15 µM

Target

S. flexneri ATCC 203

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
15 µM

Target

Escherichia coli D21

Source & Reference

dbAMP

Other

Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (
Evidence 3 Activity

Activity

MIC
Antibacterial
1.9 µM

Target

B. megateriun B11

Source & Reference

dbAMP

Other

is OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus
Evidence 4 Activity

Activity

MIC
Antibacterial
15 µM

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP

Other

E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a syn
Evidence 5 Activity

Activity

MIC
Antibacterial
12.8 µM

Target

M. luteus M1 11

Source & Reference

dbAMP

Other

IC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a synthetic form did not show the exactly same activity spectrum as the native
Evidence 6 Activity

Activity

MIC
Antifungal
15 µM

Target

S. flexneri ATCC 203

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC
Evidence 7 Activity

Activity

MIC
Antifungal
15 µM

Target

Escherichia coli D21

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (
Evidence 8 Activity

Activity

MIC
Antifungal
1.9 µM

Target

B. megateriun B11

Source & Reference

dbAMP CAFPdb Antifungipept

Other

is OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus
Evidence 9 Activity

Activity

MIC
Antifungal
15 µM

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a syn
Evidence 10 Activity

Activity

MIC
Antifungal
12.8 µM

Target

M. luteus M1 11

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a synthetic form did not show the exactly same activity spectrum as the native
Evidence 11 Activity

Activity

MIC
Antiparasitic
15 µM

Target

S. flexneri ATCC 203

Source & Reference

NA

Other

Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC
Evidence 12 Activity

Activity

MIC
Antiparasitic
15 µM

Target

Escherichia coli D21

Source & Reference

NA

Other

Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (
Evidence 13 Activity

Activity

MIC
Antiparasitic
1.9 µM

Target

B. megateriun B11

Source & Reference

NA

Other

is OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus
Evidence 14 Activity

Activity

MIC
Antiparasitic
15 µM

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a syn
Evidence 15 Activity

Activity

MIC
Antiparasitic
12.8 µM

Target

M. luteus M1 11

Source & Reference

NA

Other

IC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a synthetic form did not show the exactly same activity spectrum as the native
Evidence 16 Activity

Activity

MIC
Antiviral
15 µM

Target

S. flexneri ATCC 203

Source & Reference

NA

Other

Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC
Evidence 17 Activity

Activity

MIC
Antiviral
15 µM

Target

Escherichia coli D21

Source & Reference

NA

Other

Active against S. flexneri ATCC 203 (MIC 15 uM), P-vulgaris OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (
Evidence 18 Activity

Activity

MIC
Antiviral
1.9 µM

Target

B. megateriun B11

Source & Reference

NA

Other

is OX19 ATCC 6380 (MIC >20 uM), E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus
Evidence 19 Activity

Activity

MIC
Antiviral
15 µM

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

E. coli D21 (MIC 15 uM), P-aeruginosa OT 97 (MIC >20 uM), B. megateriun B11 (MIC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a syn
Evidence 20 Activity

Activity

MIC
Antiviral
12.8 µM

Target

M. luteus M1 11

Source & Reference

NA

Other

IC 1.9 uM), B. subtilis ATCC 6633 (MIC 15 uM), S-aureus Cowan 1 or JC-1 (MIC >20 uM), and M. luteus M1 11 (MIC 12.8 uM). Warning: a synthetic form did not show the exactly same activity spectrum as the native
Evidence 21 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antifungal activity and pore-forming mechanism of astacidin 1 against Candida albicans. | Biochimie | 2014