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Peptide record

TPDB08346

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08346
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifp Antifungipept APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AVDLAKIANKVLSSLF
Physicochemical Analysis
C78H133N19O22
RCEQGHMPTWY
AL
1689.03
9.88
2
1
10
+1
0.40
1.006
152.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
0
R
1
N
1
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
2
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 2 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
16
C78H133N19O22
1689.03
9.88
+1
0.40
1.006
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 37.5 uM) but not S.aureus (MIC >150 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 37.5 uM) but not S.aureus (MIC >150 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
37.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 37.5 uM) but not S.aureus (MIC >150 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. coli (MIC 37.5 uM) but not S.aureus (MIC >150 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
37.5 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 37.5 uM) but not S.aureus (MIC >150 uM).
Evidence 6 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

S.aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 37.5 uM) but not S.aureus (MIC >150 uM).
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
50% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning and sequence analyses of preprotemporin mRNAs containing premature stop codons from extradermal tissues of Rana tagoi. | Peptides | 2006
Evidence 8 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.