Back to search

Peptide record

TPDB08295

Antibacterial Anticancer Antifungal modified_plain modified
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB08295
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept CAFPdb dbAMP
modified_plain
Yes
A 16-aa modified multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GLFAVIKKVAAVIKKL-NH2
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
16 reviewed residue count
Amidation Activity
L Activity
Linear Activity
Free Activity
Antimicrobial and Anticancer Activity
Amphibian skin secretions Activity
Evidence Records 9 records
Evidence 1 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Leukemia Cancer
Leukemia tumor cellline
Blood

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Lung Cancer
Lung tumor cellline
Lung

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 3 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Colon Cancer
Colon tumor cellline
Colon

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 4 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Brain Tumor
Brain tumor cellline
Brain

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 5 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Skin Cancer
Skin tumor cellline
Skin

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 6 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Ovarian Cancer
Ovary tumor cellline
Ovary

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 7 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Liver Cancer
Liver tumor celline
Liver

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 8 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Prostate Cancer
Prostate tumor cellline
Prostate

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 9 Activity

Activity

IC50
IC50= 5 M
Anticancer
5

Target

Breast Cancer
Breast tumor cellline
Breast

Assay & Model

Sulforhodamine B assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003