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Peptide record

TPDB08292

Antibacterial Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08292
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FFPLIPGVRCKILRTC
Physicochemical Analysis
C87H143N23O18S2
ANDEQHMSWY
RCILFP
1863.36
10.12
3
0
7
+3
-0.75
0.887
115.62
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
6.71
3
Residue Composition
number
0
A
2
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
2
I
2
L
1
K
0
M
2
F
2
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 1 M: 0 F: 2 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C87H143N23O18S2
1863.36
10.12
+3
-0.75
0.887
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S.aureus ATCC 25923 (inactive), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (inactive MIC>150 uM), K.pneumoniae 08040724 (inactive), E.coli
Evidence 2 Activity

Activity

MIC
Antifungal
37.5 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S.aureus ATCC 25923 (inactive), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (inactive MIC>150 uM), K.pneumoniae 08040724 (inactive), E.coli
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017